Recurrent
acute otitis media (more than three
episodes within 6 months or four episodes within 12 months) is generally due to
relapse or reinfection, although data indicate that the majority of early
recurrences are new infections. In general, the same pathogens responsible for
acute otitis media cause recurrent disease; even so, the recommended treatment
consists of antibiotics active against ß-lactamase-producing
organisms. Antibiotic prophylaxis for patients with recurrent acute otitis
media [e.g., with trimethoprim-sulfamethoxazole (TMP-SMX) or amoxicillin] can
reduce recurrences by an average of one episode per year, but this benefit is
small compared with the cost of the drug and the high likelihood of
colonization with antibiotic-resistant pathogens. Other approaches, including
placement of tympanostomy tubes, adenoidectomy, and tonsillectomy plus adenoidectomy,
are of questionable overall value, given the relatively small benefit compared
with the potential for complications.
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