Reactional States Of Leprosy

Lepra reactions comprise several common immunologically mediated inflammatory states that cause considerable morbidity. Some of these reactions precede diagnosis and the institution of effective antimicrobial therapy. Indeed, these reactions may precipitate presentation for medical attention and diagnosis; others occur after the initiation of appropriate chemotherapy. In the latter circumstances, patients often lose confidence in conventional therapy, perceiving that their leprosy is worsening. Only by warning patients of the potential for these reactions and describing their manifestations can physicians treating leprosy patients ensure continued credibility.

Source: Harrison_s_Principles_of_Internal_Medicine_16th_Edition